Please use this identifier to cite or link to this item:
http://hdl.handle.net/11054/2798
Title: | DOTATATE PET-avid clear cell stromal tumour of the lung with YAP1::TFE3 fusion: Report of first Australian case. |
Author: | Yao, Scarlett Wallace, Sharon Mitchell, C. Frederick, N. McEvoy, C. Choong, D. Faisal, Wasek |
Issue Date: | 2024 |
Publication Title: | Oncology and Cancer Case Reports |
Volume: | 10 |
Issue: | 3 |
Start Page: | 1 |
Abstract: | Clear Cell Stromal Tumour of the Lung (CCST-L) is a recently recognised rare lung neoplasm, with only 19 cases reported in the current literature. Its histogenesis and pathogenesis remain largely unknown, however recent studies demonstrated the recurrent finding of YAP1::TFE3 fusion, highlighting its likely contribution to the pathogenesis. Currently, the diagnosis of CCST-L is confirmed with histological findings, exclusion of lineage-specific differentiation on immunohistochemical staining and molecular testing. With previous reports of progressive disease and mortality from distant metastasis, CCST-L posts the potential of rapid progression. Currently, no general consensus has been reached for the implication of neoadjuvant or adjuvant chemotherapy in CCST-L. Its rarity also presents the difficulty in obtaining long-term follow-up and prognostication data. We herein present the first Australian case of CCST-L with YAP1::TFE3 fusion and the first CCST-L case with DOTATATE avidity to extend our knowledge on this disease entity. |
URI: | http://hdl.handle.net/11054/2798 |
Internal ID Number: | 02818 |
Health Subject: | CLEAR CELL STROMAL TUMOUR OF THE LUNG (CCST-L) YAP1::TFE3 FUSION DOTATATE POSITRON EMISSION TOMOGRAPHY (PET) LUNG CANCER CASE STUDY |
Type: | Journal Article Article |
Appears in Collections: | Research Output |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.