Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/2013
Title: Vitamin E in cancer treatment: A review of clinical applications in randomized control trials.
Author: Donnelly, J.
Appathurai, A.
Yeoh, H-L.
Driscoll, K.
Faisal, Wasek
Issue Date: 2022
Publication Title: Nutrients
Volume: 14
Issue: 20
Start Page: 4329
Abstract: Vitamin E, along with other vitamins and micronutrients play a range of physiologic roles in the homeostasis of the body. Moreover, they also have postulated therapeutic roles that are often incompletely studied and understood. In this scoping review, we explored the recent randomized control trials (RCTs) of Vitamin E in the context of cancer, to investigate whether Vitamin E has a therapeutic role. We searched major bibliographic electronic databases to identify sixteen RCTs studying the role of Vitamin E in cancer management that have been published in the last ten years. These studies had different methodological qualities, including some that used Vitamin E in combination with other treatments. Furthermore, due to the heterogenous results, it is difficult to make a consensus statement on the effectiveness of Vitamin E in cancer therapeutics. In some cases, there were even suggestion of detriment with Vitamin E supplementation. Therefore, well designed, large, prospective RCTs are needed studying pure isoforms of Vitamin E to establish the safety and efficacy of this dietary supplement.
URI: http://hdl.handle.net/11054/2013
DOI: https://doi.org/10.3390/nu14204329
Internal ID Number: 01971
Health Subject: VITAMIN E
TOCOPHEROL
NUTRITION
CANCER
MALIGNANCY
NEOPLASM
SCOPING REVIEW
RANDOMIZED CONTROLLED TRIAL
Type: Journal Article
Article
Appears in Collections:Research Output

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