Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1922
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dc.contributorNeto, A.en_US
dc.contributorFujii, T.en_US
dc.contributorMoore, J.en_US
dc.contributorYoung, P.en_US
dc.contributorPeake, S.en_US
dc.contributorBailey, M.en_US
dc.contributorHodgson, C.en_US
dc.contributorHiggins, A.en_US
dc.contributorSee, E.en_US
dc.contributorSecombe, P.en_US
dc.contributorRuss, V.en_US
dc.contributorCampbell, L.en_US
dc.contributorYoung, M.en_US
dc.contributorMaeda, M.en_US
dc.contributorPilcher, D.en_US
dc.contributorCooper, J.en_US
dc.contributorUdy, A.en_US
dc.date.accessioned2022-06-01T06:30:03Z-
dc.date.available2022-06-01T06:30:03Z-
dc.date.issued2022-
dc.identifier.govdoc01902en_US
dc.identifier.urihttp://hdl.handle.net/11054/1922-
dc.descriptionIncludes data from BHS and WHCGen_US
dc.description.abstractObjective: To assess the incidence and impact of metabolic acidosis in Indigenous and non-Indigenous patients. <br /><br /> Design: Retrospective study. <br /><br /> Setting: Adult intensive care units (ICUs) from Australia and New Zealand. <br /><br /> Participants: Patients aged 16 years or older admitted to an Australian or New Zealand ICU in one of 195 contributing ICUs between January 2019 and December 2020 who had metabolic acidosis, defined as pH < 7.30, base excess (BE) < −4 mEq/L and PaCO2 <= 45 mmHg. Main outcome measures: The primary outcome was the prevalence of metabolic acidosis. Secondary outcomes included ICU length of stay, hospital length of stay, receipt of renal replacement therapy (RRT), major adverse kidney events at 30 days (MAKE30), and hospital mortality. <br /><br /> Results: Overall, 248 563 patients underwent analysis, with 11 537 (4.6%) in the Indigenous group and 237 026 (95.4%) in the non-Indigenous group. The prevalence of metabolic acidosis was higher in Indigenous patients (9.3% v 6.1%; P < 0.001). Indigenous patients with metabolic acidosis received RRT more often (28.2% v 22.0%; P < 0.001), but hospital mortality was similar between the groups (25.8% in Indigenous v 25.8% in non-Indigenous; P = 0.971). <br /><br /> Conclusions: Critically ill Indigenous ICU patients are more likely to have a metabolic acidosis in the first 24 hours of their ICU admission, and more often received RRT during their ICU admission compared with non-Indigenous patients. However, hospital mortality was similar between the groups.en_US
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2022-05-11T03:50:36Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2022-06-01T06:30:02Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2022-06-01T06:30:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2022en
dc.titleClinical outcomes of Indigenous Australians and New Zealand Maori with metabolic acidosis and acidaemia.en_US
dc.typeJournal Articleen_US
dc.type.specifiedArticleen_US
dc.bibliographicCitation.titleCritical Care and Resuscitationen_US
dc.bibliographicCitation.volume24en_US
dc.bibliographicCitation.issue1en_US
dc.bibliographicCitation.stpage14en_US
dc.bibliographicCitation.endpage18en_US
dc.subject.healththesaurusINDIGENOUS PEOPLESen_US
dc.subject.healththesaurusMETABOLIC ACIDOSISen_US
dc.identifier.doihttps://doi.org/10.51893/2022.1.OA2en_US
Appears in Collections:Research Output

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