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http://hdl.handle.net/11054/1845
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DC Field | Value | Language |
---|---|---|
dc.contributor | Javaid, Aanadil | en_US |
dc.contributor | Mathai, Jared | en_US |
dc.contributor | Song, David | en_US |
dc.contributor | Brown, Stephen | en_US |
dc.date.accessioned | 2022-01-27T04:02:58Z | - |
dc.date.available | 2022-01-27T04:02:58Z | - |
dc.date.issued | 2022 | - |
dc.identifier.govdoc | 01864 | en_US |
dc.identifier.uri | http://hdl.handle.net/11054/1845 | - |
dc.description.abstract | Sunitinib is a tyrosine kinase inhibitor that is frequently used in the treatment of metastatic renal cell carcinoma (mRCC). As a multikinase inhibitor, numerous off-target side effects of this medication are widely recognized. More recently, endocrine side effects, including hypoadrenalism, are becoming more apparent. We report a case in which a 71-year-old female experienced recurrent adrenal crises when managed with sunitinib for mRCC on a background of immune-related hypopituitarism and hypoadrenalism as a result of previous treatment with immunotherapy. Clinicians should be aware of this potential toxicity when using such medications and consider further investigation in the appropriate clinical setting. | en_US |
dc.description.provenance | Submitted by Gemma Siemensma (gemmas@bhs.org.au) on 2022-01-17T22:55:45Z No. of bitstreams: 0 | en |
dc.description.provenance | Approved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2022-01-27T04:02:58Z (GMT) No. of bitstreams: 0 | en |
dc.description.provenance | Made available in DSpace on 2022-01-27T04:02:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2022 | en |
dc.title | Sunitinib-induced adrenal crisis in a patient with pre-existing immunotherapy-related hypopituitarism. | en_US |
dc.type | Journal Article | en_US |
dc.type.specified | Article | en_US |
dc.bibliographicCitation.title | Case Reports in Oncology | en_US |
dc.bibliographicCitation.volume | 15 | en_US |
dc.bibliographicCitation.stpage | 1 | en_US |
dc.bibliographicCitation.endpage | 6 | en_US |
dc.subject.healththesaurus | SUNITINIB | en_US |
dc.subject.healththesaurus | HYPOADRENALISM | en_US |
dc.subject.healththesaurus | ADRENAL CRISIS | en_US |
dc.subject.healththesaurus | IMMUNOTHERAPY SIDE EFFECTS | en_US |
dc.identifier.doi | https://doi.org/10.1159/000521206 | en_US |
Appears in Collections: | Research Output |
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