Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1845
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dc.contributorJavaid, Aanadilen_US
dc.contributorMathai, Jareden_US
dc.contributorSong, Daviden_US
dc.contributorBrown, Stephenen_US
dc.date.accessioned2022-01-27T04:02:58Z-
dc.date.available2022-01-27T04:02:58Z-
dc.date.issued2022-
dc.identifier.govdoc01864en_US
dc.identifier.urihttp://hdl.handle.net/11054/1845-
dc.description.abstractSunitinib is a tyrosine kinase inhibitor that is frequently used in the treatment of metastatic renal cell carcinoma (mRCC). As a multikinase inhibitor, numerous off-target side effects of this medication are widely recognized. More recently, endocrine side effects, including hypoadrenalism, are becoming more apparent. We report a case in which a 71-year-old female experienced recurrent adrenal crises when managed with sunitinib for mRCC on a background of immune-related hypopituitarism and hypoadrenalism as a result of previous treatment with immunotherapy. Clinicians should be aware of this potential toxicity when using such medications and consider further investigation in the appropriate clinical setting.en_US
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2022-01-17T22:55:45Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2022-01-27T04:02:58Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2022-01-27T04:02:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2022en
dc.titleSunitinib-induced adrenal crisis in a patient with pre-existing immunotherapy-related hypopituitarism.en_US
dc.typeJournal Articleen_US
dc.type.specifiedArticleen_US
dc.bibliographicCitation.titleCase Reports in Oncologyen_US
dc.bibliographicCitation.volume15en_US
dc.bibliographicCitation.stpage1en_US
dc.bibliographicCitation.endpage6en_US
dc.subject.healththesaurusSUNITINIBen_US
dc.subject.healththesaurusHYPOADRENALISMen_US
dc.subject.healththesaurusADRENAL CRISISen_US
dc.subject.healththesaurusIMMUNOTHERAPY SIDE EFFECTSen_US
dc.identifier.doihttps://doi.org/10.1159/000521206en_US
Appears in Collections:Research Output

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