Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributorWeon, JangHoen_US
dc.contributorRobson, Scotten_US
dc.contributorChan, R.en_US
dc.contributorUssher, Simonen_US
dc.description.abstractIntroduction: To retrospectively evaluate the incidence of and the risk factors for pneumothorax and intercostal catheter insertion (ICC) after CT-guided lung biopsy and to generate a risk prediction model for developing a pneumothorax and requiring an ICC. Methods: 255 CT-guided lung biopsies performed for 249 lesions in 249 patients from August 2014 to August 2019 were retrospectively analysed using multivariate logistic regression analysis. Risk prediction models were established using backward stepwise variable selection and likelihood ratio tests and were internally validated using split-sample methods. Results: The overall incidence of pneumothorax was 30.2% (77/255). ICC insertion was required for 8.32% (21/255) of all procedures. The significant independent risk factors for pneumothorax were lesions not in contact with pleura (P < 0.001), a shorter skin-to-pleura distance (P = 0.01), the needle crossing a fissure (P = 0.004) and emphysema (P = 0.01); those for ICC insertion for pneumothorax were a needle through emphysema (P < 0.001) and lesions in the upper lobe (P = 0.017). AUC of the predictive models for pneumothorax and ICC insertion were 0.800 (95% CI: 0.745-0.856) and 0.859 (95% CI: 0.779-0.939) respectively. Upon internal validation, AUC of the testing sets of pneumothorax and ICC insertion were 0.769 and 0.822 on average respectively. Conclusion: The complication rates of pneumothorax and ICC insertion after CT-guided lung biopsy at our institution are comparable to results from previously reported studies. This study provides highly accurate risk prediction models of pneumothorax and ICC insertion for patients undergoing CT-guided lung biopsies.en_US
dc.description.provenanceSubmitted by Gemma Siemensma ( on 2021-11-23T00:20:58Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma ( on 2021-11-30T22:41:59Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2021-11-30T22:41:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2021en
dc.titleDevelopment of a risk prediction model of pneumothorax in percutaneous computed tomography guided transthoracic needle lung biopsy.en_US
dc.typeJournal Articleen_US
dc.bibliographicCitation.titleJournal of Medical Imaging and Radiation Oncologyen_US
dc.subject.healththesaurusCT-GUIDED LUNG BIOPSYen_US
dc.subject.healththesaurusINTERCOSTAL CATHETERen_US
dc.subject.healththesaurusRISK FACTORen_US
dc.subject.healththesaurusRISK PREDICTION MODELen_US
Appears in Collections:Research Output

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.