Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1745
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dc.contributorAbdelkarim, Hussamen_US
dc.contributorCiampoli, Natashaen_US
dc.contributorZwakman-Hessels, Laraen_US
dc.contributorDarvall, Jai N.en_US
dc.contributorBellomo, Rinaldoen_US
dc.date.accessioned2021-07-23T02:21:00Z-
dc.date.available2021-07-23T02:21:00Z-
dc.date.issued2020-
dc.identifier.govdoc01693en_US
dc.identifier.urihttp://hdl.handle.net/11054/1745-
dc.description.abstractObjective: To test the effectiveness of chewing gum in the prophylaxis of postoperative nausea and vomiting (PONV) in patients admitted to the intensive care unit (ICU) after surgery. <br /><br /> Design: Prospective, open label, pilot randomised controlled trial. <br /><br /> Setting: Two metropolitan ICUs. <br /><br /> Participants: Ninety postoperative adult patients admitted to the ICU. <br /><br /> Intervention: Patients administered chewing gum, who chewed for at least 15 minutes every 4 hours, were compared with a control group, who were administered a 20 mL sip of water orally every 4 hours. <br /><br /> Main outcome measures: The primary outcome was the number of patient-reported episodes of nausea in the first 24 hours after the operation. Secondary outcomes included vomiting or dry retching episodes, and duration and severity of nausea. <br /><br /> Results: Forty-six patients were randomly allocated to chewing gum and 44 patients to water. There was no difference between groups in the number of patients with nausea (10 [22%] chewing gum v 12 [27%] control patients; P = 0.72), nausea episodes (22 episodes; [median, 0; IQR, 0-0] v 21 episodes [median, 0; IQR, 0-1] per patient in each group respectively), vomiting/retching (2 [4%] chewing gum v 6 [14%] control patients; P = 0.24), or duration/ severity of nausea. <br /><br /> Conclusion: Regular postoperative administration of chewing gum in a surgical ICU patient cohort did not reduce nausea, vomiting or retching. The prevalence of PONV is less than previously reported. Our findings can inform future studies of PONV prophylaxis in post-surgical ICU patients. <br /><br /> Trial registration: Australian New Zealand Clinical Trial Registry No. ACTRN12617001185358.en_US
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2021-05-11T04:01:06Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2021-07-23T02:21:00Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2021-07-23T02:21:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.titleChewing gum prophylaxis for postoperative nausea and vomiting in the intensive care unit: A pilot randomised controlled trial.en_US
dc.typeJournal Articleen_US
dc.type.specifiedArticleen_US
dc.bibliographicCitation.titleCritical Care and Resuscitationen_US
dc.bibliographicCitation.volume22en_US
dc.bibliographicCitation.issue4en_US
dc.bibliographicCitation.stpage321en_US
dc.bibliographicCitation.endpage326en_US
dc.subject.healththesaurusCHEWING GUMen_US
dc.subject.healththesaurusPOSTOPERATIVE NAUSEA AND VOMITINGen_US
dc.subject.healththesaurusINTENSIVE CARE UNITen_US
dc.subject.healththesaurusICUen_US
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