Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1496
Title: New predictors of atrial fibrillation is ESUS – a systematic review.
Author: Grose, Daniel
Maylin, Erin
Kraemer, Thomas
Sharma, Anand
Oqueli, Ernesto
Churilov, L
Sahathevan, Ramesh
Issue Date: 2019
Conference Name: 5th European Stroke Organisation Conference (ESOC)
Conference Date: May 22- 24
Conference Place: Milan, Italy
Abstract: Background and Aims: An increasing proportion of ischaemic strokes are classified as embolic stroke of undermined source (ESUS). It is established that approximately a third of ESUS are due to paroxysmal atrial fibrillation (AF). The diagnosis of AF can be straightforward but often requires invasive and costly cardiac monitoring. We have previously reviewed established risk-predictors of atrial fibrillation, based on an amalgam of variables such as age, sex and cardiovascular risk factors. Since development of the concept of ESUS in 2014, there have been additional and new developments in identifying singular novel predictors. We sought to identify and summarise novel predictors of atrial fibrillation to inform the development of a new clinical tool to assess the risk and perhaps predict atrial fibrillation following ESUS. Methods: A systematic review of the literature was preformed to identify studies that examined singular predictors of atrial fibrillation published from 2014 onwards. Results: A total of 29 articles were identified from more than 130 that met our search criteria articles. Conclusions: Newly validated measurements based on electrocardiogram and echocardiogram have been identified to predict AF in stroke patients. In addition we identified biomarkers of AF including several intrinsic cardiac hormones. These new potential markers of AF in stroke should be combined with more traditional risk predictors to develop a new tool to assess the individuals’ risk of AF following ESUS. This would guide the need for further cardiac monitoring and aid risk-stratification of patients who might benefit from the use of direct oral anticoagulants.
URI: http://hdl.handle.net/11054/1496
Internal ID Number: 01350
Health Subject: PAROXYSMAL ATRIAL FIBRILLATION
CARDIAC MONITORING
RISK PREDICTORS
EMBOLIC STROKE OF UNDERMINED SOURCE
CARDIAC HORMONES
BIOMARKERS
Type: Conference
Poster
Appears in Collections:Research Output

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