Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributorNoaman, S.en_US
dc.contributorAndrianopoulos, N.en_US
dc.contributorBrennan, A.en_US
dc.contributorReid, C.en_US
dc.contributorStub, D.en_US
dc.contributorBiswas, S.en_US
dc.contributorWalton A.en_US
dc.contributorClark, D.en_US
dc.contributorAjani, A.en_US
dc.contributorFreeman, M.en_US
dc.contributorShaw, J.en_US
dc.contributorOqueli, Ernestoen_US
dc.contributorYip, T.en_US
dc.contributorDuffy, S.en_US
dc.contributorChan, W.en_US
dc.description.abstractBackground : Cardiogenic shock (CS) complicates ∼5% of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI), with the highest mortality in certain subgroups despite contemporary ACS treatment. Methods: Patients with ACS enrolled in the Melbourne Interventional Group registry (2005–2013) with CS ( n = 636) were analysed according to pre-specified subgroups. Those with STEMI were compared to non-STEMI, and multivessel PCI compared to single-vessel PCI. Short-term MACE (death, MI, target-vessel revascularisation) and long-term National Death Index (NDI)-linked mortality were assessed between the subgroups. Results: Patients with CS presented with high rates of STEMI (89%) and a preponderance of multivessel disease (70%), however, only 12% underwent multivessel PCI. In-hospital and 30-day MACE were high in the CS cohort (46% and 47% respectively). Long-term NDI-linked mortality was 51% in the entire CS cohort. Subgroup analyses revealed greater in-hospital, 30-day and NDI-linked mortality among those who presented with non-STEMI compared to those with STEMI (63% vs. 38%, 64% vs. 38%, and 79% vs. 47%, respectively, all p < 0.01). There was a trend towards higher in-hospital and 30-day mortality among those who underwent multivessel PCI (50% vs. 39%, p = 0.07 and 50% vs. 40%, p = 0.09). Higher long-term NDI-linked mortality was observed in the multivessel PCI subgroup (63% vs. 49%, p < 0.05). Conclusion: Cardiogenic shock complicating ACS portends very poor short and long-term survival with particularly high mortality in the non-STEMI and multivessel PCI subgroups.en_US
dc.description.provenanceSubmitted by Gemma Siemensma ( on 2019-07-30T04:22:54Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma ( on 2019-10-16T03:09:06Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2019-10-16T03:09:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.titleCharacteristics of patients with cardiogenic shock complicating acute coronary syndrome and its influence on clinical outcomes.en_US
dc.bibliographicCitation.conferencedateAugust 8th-11then_US
dc.bibliographicCitation.conferencename67th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 13th Annual Australia and New Zealand Endovascular Therapies Meeting.en_US
dc.bibliographicCitation.conferenceplaceAdelaide, Australiaen_US
dc.subject.healththesaurusCARDIOGENIC SHOCKen_US
dc.subject.healththesaurusACUTE CORONARY SYNDROMEen_US
dc.subject.healththesaurusMELBOURNE INTERVENTIONAL GROUPen_US
Appears in Collections:Research Output

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.