Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1406
Full metadata record
DC FieldValueLanguage
dc.contributorSiriratnam, Pakeeranen_US
dc.contributorKraemer, Thomasen_US
dc.contributorSahathevan, Rameshen_US
dc.date.accessioned2019-10-14T08:58:17Z-
dc.date.available2019-10-14T08:58:17Z-
dc.date.issued2019-
dc.identifier.govdoc01379en_US
dc.identifier.urihttp://hdl.handle.net/11054/1406-
dc.description.abstractAbstract Background: Although there is an established association between cancer and stroke, the role of malignancy as a causative agent or comorbidity is not always clear. Moreover, there are no established guidelines on the acute treatment of cancer-associated stroke or optimal anticoagulation. This case report illustrates the significance of these practice gaps. Case presentation: A 62-year-old Caucasian woman presented to our institute with acute neurological deficits and was found to have an occluded left middle cerebral artery on a computed tomographic angiogram. She was administered intravenous alteplase and underwent unsuccessful endovascular clot retrieval. Besides smoking and her age, she had no cerebrovascular risk factors, and the results of baseline investigations for the cause of stroke were negative. Subsequent computed tomography of the chest, abdomen, and pelvis showed metastatic malignancy, and in the context of a significantly elevated serum cancer antigen 19-9, we suspected a pancreatic primary cancer. A transthoracic echocardiogram demonstrated mitral regurgitation but no visible vegetation. The patient died of her illness. We made a diagnosis of cancer-associated stroke, specifically a likely case of nonbacterial thrombotic endocarditis. Conclusions: This case highlights the importance of having a high threshold of suspicion for malignancy as a cause of stroke.en_US
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2019-08-27T05:17:50Z No. of bitstreams: 1 Stroke in malignancy_complexities of diagnosis and management_a case report..pdf: 1789182 bytes, checksum: 4e13b5e57a901aa116edb07b5ee0edf0 (MD5)en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2019-10-14T08:58:17Z (GMT) No. of bitstreams: 1 Stroke in malignancy_complexities of diagnosis and management_a case report..pdf: 1789182 bytes, checksum: 4e13b5e57a901aa116edb07b5ee0edf0 (MD5)en
dc.description.provenanceMade available in DSpace on 2019-10-14T08:58:17Z (GMT). No. of bitstreams: 1 Stroke in malignancy_complexities of diagnosis and management_a case report..pdf: 1789182 bytes, checksum: 4e13b5e57a901aa116edb07b5ee0edf0 (MD5) Previous issue date: 2019en
dc.relation.urihttps://doi.org/10.1186/s13256-019-2183-8en_US
dc.titleStroke in malignancy: complexities of diagnosis and management: a case report.en_US
dc.typeJournal Articleen_US
dc.type.specifiedArticleen_US
dc.bibliographicCitation.titleJournal of Medical Case Reportsen_US
dc.bibliographicCitation.volume13en_US
dc.bibliographicCitation.issue1en_US
dc.bibliographicCitation.stpage260en_US
dc.subject.healththesaurusANTITHROMBOTIC SUBSTANCESen_US
dc.subject.healththesaurusPROCOAGULANT SUBSTANCESen_US
dc.subject.healththesaurusINFLAMMATORY CYTOKINESen_US
dc.subject.healththesaurusMICROPARTICLESen_US
dc.subject.healththesaurusDECONDENSED CHROMATINen_US
dc.subject.healththesaurusNONBACTERIAL THROMBOTIC ENDOCARDITISen_US
Appears in Collections:Research Output

Files in This Item:
File Description SizeFormat  
Stroke in malignancy_complexities of diagnosis and management_a case report..pdfJournal article1.75 MBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.