Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/6
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHurley, James C.*
dc.date.accessioned2012-08-06T23:23:49Zen
dc.date.available2012-08-06T23:23:49Zen
dc.date.issued2011en
dc.identifier.govdoc00007en
dc.identifier.issn0003-9985en
dc.identifier.urihttp://hdl.handle.net/11054/6en
dc.description.abstractAbstract: Meta-analytic summaries are needed on clinical studies of diagnostic tests. Meta-analyses on clinical studies of diagnostic tests commonly use the receiver operating characteristic method, which differs conceptually and computationally from the more widely known meta-analytic methods applicable in other contexts, such as in studies of randomized controlled trials. Important conceptual differences for clinical studies of diagnostic tests versus randomized controlled trials are that the study subpopulations are not defined by random allocation and the test threshold typically varies across studies to accommodate "rule in" versus "rule out" testing strategies. The receiver operating characteristic method has evolved substantially in the past decade, and the most recent approaches use multilevel regression methods that require iterative computational solutions to estimate the influence of the study-level variables. Using current methodology, a meta-analysis on clinical studies of diagnostic tests can address questions relevant to the clinical application of a diagnostic test that cannot be answered at the level of the individual study.en
dc.description.provenanceApproved for entry into archive by Kimberley Asprey (kimberleya@bhs.org.au) on 2012-08-06T23:23:49Z (GMT) No. of bitstreams: 0en
dc.description.provenanceSubmitted by Kimberley Asprey (kimberleya@bhs.org.au) on 2012-08-06T23:22:09ZNo. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2012-08-06T23:23:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2011en
dc.publisherCollege of American Pathologists.en
dc.relation.urihttp://www.archivesofpathology.org/doi/abs/10.5858/arpa.2011-0016-SO?prevSearch=Meta-analysis+of+clinical+studies+of+diagnostic+tests%3A+developments+in+how+the+receiver+operating+characteristic+%22works%22&searchHistoryKey=en
dc.titleMeta-analysis of clinical studies of diagnostic tests: developments in how the receiver operating characteristic "works".en
dc.typeJournal Articleen
dc.type.specifiedArticleen
dc.bibliographicCitation.titleArchives of Pathology & Laboratory Medicine.en
dc.bibliographicCitation.volume135en
dc.bibliographicCitation.issue12en
dc.bibliographicCitation.stpage1585en
dc.bibliographicCitation.endpage1590en
dc.subject.healththesaurusDIAGNOSTIC TESTSen
dc.subject.healththesaurusMETA ANALYSIS AS A TOPICen
dc.subject.healththesaurusCLINICAL STATISTICS AND NUMERICAL DATAen
dc.date.issuedbrowse2011-01-01en
Appears in Collections:Research Output

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.