Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/269
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dc.contributor.authorWestbrook, A.en
dc.contributor.authorPettila, V.en
dc.contributor.authorNichol, A.en
dc.contributor.authorBailey, M. J.en
dc.contributor.authorSyres, G.en
dc.contributor.authorMurray, L.en
dc.contributor.authorBellomo, R.en
dc.contributor.authorWood, E.en
dc.contributor.authorPhillips, L. E.en
dc.contributor.authorStreet, A.en
dc.contributor.authorFrench, C.en
dc.contributor.authorOrford, N.en
dc.contributor.authorSantamaria, J.en
dc.contributor.authorCooper, D. J.en
dc.date.accessioned2013-05-29T03:19:28Zen
dc.date.available2013-05-29T03:19:28Zen
dc.date.issued2010en
dc.identifier.govdoc00267en
dc.identifier.issn0342-4642en
dc.identifier.urihttp://hdl.handle.net/11054/269en
dc.description.abstractObjective To describe the relationship between clinical practice and national guidelines for the transfusion of red blood cells (RBCs), fresh frozen plasma (FFP), platelets, and cryoprecipitate in Australian and New Zealand intensive care units (ICUs). Setting Forty-seven ICUs over a 5-week period from August to September 2008. Design Prospective, observational, multicentre, cohort study. Patients A total of 874 patients receiving any type of blood transfusion. Methods All patients who were transfused at least one unit of any blood component were included. Patient-specific and blood-component specific data were gathered. Pre-transfusion haemoglobin, platelet count, international normalised ratio (INR), and fibrinogen levels were compared to national guidelines. Results Of all 874 patients, 757 received RBCs (86.6%), 231 (26.4%) received platelets, 340 (38.9%) received FFP, and 78 (8.9%) received cryoprecipitate. Bleeding was the reason for administration of RBCs in 46%, FFP in 55%, and platelets in 47% of transfusions. The mean (SD) pre-transfusion haemoglobin was 77.6 (9.5) g/l, while the geometric means (95% CI) for platelet count, INR, and fibrinogen were 67.0 (59.7–75.3) × 109/l, 1.84 (1.76–1.93), and 1.4 (1.1–1.8) g/l, respectively. The proportions of transfusions not adherent to guidelines were 2% for RBC, but 53% for platelets, 29% for FFP, and 88% for cryoprecipitate (RBC vs. other transfusion p < 0.001 for all). Conclusions Transfusion practice of RBCs in Australian and New Zealand ICUs is restrictive and is concordant with guidelines. However, the transfusion of other blood components is not. This study was conducted with data obtained from Ballarat Health Services - R. Gazzard; C. Tauschke; D. Hill.en
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2013-05-27T04:39:52Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2013-05-29T03:19:28Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2013-05-29T03:19:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2010en
dc.publisherSpringer Verlagen
dc.relation.urihttp://rd.springer.com/article/10.1007%2Fs00134-010-1867-8#en
dc.titleTransfusion practice and guidelines in Australian and New Zealand intensive care units.en
dc.typeJournal Articleen
dc.type.specifiedArticleen
dc.contributor.corpauthorANZICS Clinical Trials Groupen
dc.bibliographicCitation.titleIntensive Care Medicineen
dc.bibliographicCitation.volume36en
dc.bibliographicCitation.issue7en
dc.bibliographicCitation.stpage1138en
dc.bibliographicCitation.endpage1146en
dc.publisher.placeGermanyen
dc.subject.healththesaurusICUen
dc.subject.healththesaurusTRANSFUSIONen
dc.subject.healththesaurusRED BLOOD CELLSen
dc.subject.healththesaurusFRESH FROZEN PLASMAen
dc.subject.healththesaurusPLATELETSen
dc.subject.healththesaurusCRYOPRECIPITATEen
dc.subject.healththesaurusINDICATIONen
dc.subject.healththesaurusBLOODen
dc.subject.healththesaurusCLINICAL TRIALen
dc.subject.healththesaurusINTENSIVE CAREen
dc.date.issuedbrowse2010-01-01en
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