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Title: TTF1 expression in advanced lung adenocarcinoma and survival outcome: an observational study.
Author: Webster, R.
McCann, Kathy
Facey, M.
Faisal, Wasek
Issue Date: 2021
Conference Name: 2021 World Conference on Lung Cancer
Conference Date: September 8-14
Conference Place: Online
Abstract: Prognosis of advanced lung adenocarcinoma remains poor despite significant advances in treatment options. Current literature calls for independent prognostic biomarkers to better stratify patient risk. Thyroid transcription factor 1 (TTF1) is regulatory protein that is suggested to be a favourable prognostic indicator independent of stage at diagnosis. The mechanism for this remains unclear with loss of differentiation of tumour a possible explanation. Further research, however, is needed for clinical application. This study explores TTF1 expression in adenocarcinoma of the lung and its correlation to survival outcomes as well as explores patterns of incidence in relation to tumour grade, gain of function mutations and PD-L1 status.
Internal ID Number: 01784
Health Subject: LUNG CANCER
Type: Conference
Appears in Collections:Research Output

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