Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1577
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dc.contributorSecombe, P.en_US
dc.contributorWoodman, R.en_US
dc.contributorChan, S.en_US
dc.contributorPilcher, D.en_US
dc.contributorvan Haren, F.en_US
dc.date.accessioned2020-08-10T09:30:08Z-
dc.date.available2020-08-10T09:30:08Z-
dc.date.issued2020-
dc.identifier.govdoc01510en_US
dc.identifier.urihttp://hdl.handle.net/11054/1577-
dc.descriptionIncludes data from BHSen_US
dc.description.abstractObjective: The apparent survival benefit of being overweight or obese in critically ill patients (the obesity paradox) remains controversial. Our aim is to report on the epidemiology and outcomes of obesity within a large heterogenous critically ill adult population. Design: Retrospective observational cohort study. Setting: Intensive care units (ICUs) in Australia and New Zealand. Participants: Critically ill patients who had both height and weight recorded between 2010 and 2018. Outcome measures: Hospital mortality in each of five body mass index (BMI) strata. Subgroups analysed included diagnostic category, gender, age, ventilation status and length of stay. Results: Data were available for 381 855 patients, 68% of whom were overweight or obese. Increasing level of obesity was associated with lower unadjusted hospital mortality: underweight (11.9%), normal weight (7.7%), overweight (6.4%), class I obesity (5.4%), and class II obesity (5.3%). After adjustment, mortality was lowest for patients with class I obesity (adjusted odds ratio, 0.78; 95% CI, 0.74- 0.82). Adverse outcomes with class II obesity were only seen in patients with cardiovascular and cardiac surgery ICU admission diagnoses, where mortality risk rose with progressively higher BMIs. Conclusion: We describe the epidemiology of obesity within a critically ill Australian and New Zealand population and confirm that some level of obesity is associated with lower mortality, both overall and across a range of diagnostic categories and important subgroups. Further research should focus on potential confounders such as nutritional status and the appropriateness of BMI in isolation as an anthropometric measure in critically ill patients.en_US
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2020-08-03T02:17:50Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2020-08-10T09:30:08Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2020-08-10T09:30:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2020en
dc.titleEpidemiology and outcomes of obese critically ill patients in Australia and New Zealand.en_US
dc.typeJournal Articleen_US
dc.type.specifiedArticleen_US
dc.bibliographicCitation.titleCritical Care and Resuscitationen_US
dc.bibliographicCitation.volume22en_US
dc.bibliographicCitation.issue1en_US
dc.bibliographicCitation.stpage35en_US
dc.bibliographicCitation.endpage44en_US
dc.subject.healththesaurusBODY MASS INDEXen_US
dc.subject.healththesaurusEPIDEMIOLOGYen_US
dc.subject.healththesaurusCRITICALLY ILLen_US
dc.subject.healththesaurusOVERWEIGHT PERSONSen_US
dc.subject.healththesaurusPATIENTS--CAREen_US
dc.subject.healththesaurusINTENSIVE CARE UNITSen_US
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