Please use this identifier to cite or link to this item:
|Is selective decontamination (SDD/SOD) safe in the ICU context?
|Hurley, James C.
|Journal of Antimicrobial Chemotherapy
|Multiple individual studies of selective digestive decontamination/selective oropharyngeal decontamination (SDD/SOD) among ICU patients appear to show potent infection prevention effects. Surprisingly, the event rates for multiple endpoints including ventilator-associated pneumonia, bacteraemia and candidaemia among concurrent control groups within SDD/SOD studies appear unusually high versus other rates in the literature. These paradoxical observations raise concern that the contextual effects of SDD/SOD, as postulated in the original SDD/SOD study, not only exist but also are strong. Until these effects are addressed within an optimally designed study, the safety of SDD/SOD within the ‘whole of ICU’ remains questionable.
|Internal ID Number:
|SELECTIVE DIGESTIVE DECONTAMINATION
SELECTIVE OROPHARYNGEAL DECONTAMINATION
|Appears in Collections:
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.