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http://hdl.handle.net/11054/1179
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DC Field | Value | Language |
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dc.contributor | Noaman, Samer | en_US |
dc.contributor | Adrianopoulos, Nick | en_US |
dc.contributor | Reid, C. | en_US |
dc.contributor | Sharma, Anand | en_US |
dc.contributor | Chan, W. | en_US |
dc.contributor | O'Brien, Joseph | en_US |
dc.contributor | Clark, D. | en_US |
dc.contributor | Freeman, M. | en_US |
dc.contributor | Ajani, A. | en_US |
dc.contributor | Brennan, A. | en_US |
dc.contributor | Yip, T. | en_US |
dc.contributor | Duffy, S. | en_US |
dc.contributor | Oqueli, Ernesto | en_US |
dc.date.accessioned | 2018-07-27T01:48:58Z | - |
dc.date.available | 2018-07-27T01:48:58Z | - |
dc.date.issued | 2017 | - |
dc.identifier.govdoc | 01127 | en_US |
dc.identifier.uri | http://hdl.handle.net/11054/1179 | - |
dc.description.abstract | Background: Previous studies suggest that rates of morbidity and mortality are higher in ST-elevation myocardial infarction (STEMI) caused by stent thrombosis (ST) compared to those caused by a de novo lesion. Methods: We studied data from 3,963 patients presenting with STEMI enrolled in the Melbourne Interventional Group registry between 2009 and 2016. They were divided into definite ST group (n = 128) and de novo group (n = 3,835). Short and long-term outcomes were compared. Results: Compared to the de novo group, patients with ST had higher rates of previous myocardial infarction (82% vs. 8.6%, p < 0.001). The majority of ST were very late (>365 days), followed by late (31-365 days) and early ST (64%, 19% and 17%), respectively. Interestingly, the ST group presented with less out-of-hospital cardiac arrest (OHCA) (4.7% vs. 11.5%, p < 0.01) and had shorter symptom-onset-to-door time (STDT), median (IQR) (101 min, 71-162 vs. 114 min, 75- 210, p = 0.03) with no differences in door-to-balloon time, median (IQR) (66 min, 43-79 vs. 67 min, 44-96, p = 0.9), leading to shorter symptom-to-balloon time, median (IQR) (184 min, 132-239 vs. 194 min, 141-291, p = 0.051). There were no significant differences between outcomes for in-hospital, 30-day, 12-months and (NDI-linked) long-term mortality between the two groups. ST was not an independent predictor of 30-day MACE on multivariate analysis (HR 0.8, CI 0.4-1.8, p = 0.75). Conclusion: Patients presenting with STEMI caused by definite ST had similar outcomes to those caused by de novo lesions. A shorter STDT may represent earlier recognition of symptoms in the ST group and possibly contributed to their similar outcome with the de novo group. | en_US |
dc.description.provenance | Submitted by Gemma Siemensma (gemmas@bhs.org.au) on 2018-07-23T23:29:29Z No. of bitstreams: 0 | en |
dc.description.provenance | Approved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2018-07-27T01:48:58Z (GMT) No. of bitstreams: 0 | en |
dc.description.provenance | Made available in DSpace on 2018-07-27T01:48:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2017 | en |
dc.title | Clinical outcomes of ST-Elevation myocardial infarction secondary to stent thrombosis treated by percutaneous coronary intervention. | en_US |
dc.type | Conference | en_US |
dc.type.specified | Presentation | en_US |
dc.bibliographicCitation.conferencedate | August 10-13 | en_US |
dc.bibliographicCitation.conferencename | 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting | en_US |
dc.bibliographicCitation.conferenceplace | Perth, Australia | en_US |
dc.subject.healththesaurus | ST ELEVATION MYOCARDIAL INFARCTION | en_US |
dc.subject.healththesaurus | MYOCARDIAL INFARCTION | en_US |
dc.subject.healththesaurus | REGISTRIES | en_US |
dc.subject.healththesaurus | ANTERIOR WALL MYOCARDIAL INFARCTION | en_US |
dc.subject.healththesaurus | THROMBOSIS | en_US |
dc.subject.healththesaurus | STENTS | en_US |
dc.subject.healththesaurus | PERCUTANEOUS CORONARY INTERVENTION | en_US |
Appears in Collections: | Research Output |
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