Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1122
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dc.contributorRajput, Nitinen_US
dc.contributorFilipovska, Juliaen_US
dc.contributorHewson, Michaelen_US
dc.date.accessioned2018-04-11T23:50:48Z-
dc.date.available2018-04-11T23:50:48Z-
dc.date.issued2017-
dc.identifier.govdoc01114en_US
dc.identifier.issn0041-4301en_US
dc.identifier.urihttp://hdl.handle.net/11054/1122-
dc.description.abstractThe effects of routine administration of probiotics on the length of central venous line usage in extremely premature infants. Turk J Pediatr 2017; 59: 20-27. The objective of this study was to determine whether the routine use of probiotics was associated with earlier removal of peripherally inserted central catheter (PICC) lines in extremely premature infants born ≤28 weeks' gestation. This study was a retrospective, observational, cohort study in infants born ≤28 weeks gestation in the 2 years before [No Probiotic Group (NPG)] and after [Probiotic Group (PG)] the commencement of the routine use of probiotics (lnfloran®) in a large tertiary neonatal intensive care unit in the North Island of New Zealand. Age at the removal of PICC line in patients whose first PICC lines were inserted before day 14 and remained in-situ for at least 4 days was compared using Kaplan-Meir Survival Analysis on SPSS 22.0®. We studied PICC line infections as a secondary outcome measure. We compared 120 PICC lines in NPG and 130 PICC lines in PG. Mean age at removal was 25.9 [(95% Confidence Intervals (CI)=22.6 - 29.2)] days in NPG and 23.1 (95% CI=20.9 - 25.2) days in PG. The result was independent of birth weight, gender, type of PICC line and age at insertion but related significantly to gestation at birth (p < 0.001). There was no difference in the incidence or the microbiologic profile of PICC line infections between the study groups. PICC lines were removed 2.8 days earlier in infants receiving probiotics (p=0.070), which can have potential benefits with reduced infection and other risks due to earlier removal of PICC lines.en_US
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2018-03-19T02:05:46Z No. of bitstreams: 0en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2018-04-11T23:50:48Z (GMT) No. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2018-04-11T23:50:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2017en
dc.titleThe effects of routine administration of probiotics on the length of central venous line usage in extremely premature infants.en_US
dc.typeJournal Articleen_US
dc.type.specifiedArticleen_US
dc.bibliographicCitation.titleThe Turkish Journal of Pediatricsen_US
dc.bibliographicCitation.volume59en_US
dc.bibliographicCitation.issue1en_US
dc.bibliographicCitation.stpage20en_US
dc.bibliographicCitation.endpage27en_US
dc.subject.healththesaurusINFANT, NEWBORNen_US
dc.subject.healththesaurusINFANT, EXTREMELY PREMATUREen_US
dc.subject.healththesaurusINTENSIVE CARE UNITS, NEONATALen_US
dc.subject.healththesaurusPROBIOTICSen_US
dc.subject.healththesaurusRETROSPECTIVE STUDIESen_US
dc.subject.healththesaurusCENTRAL VENOUS CATHETERen_US
dc.subject.healththesaurusCATHERISATION, PERIPHERALen_US
dc.subject.healththesaurusOUTCOME ASSESSMENT (HEALTH CARE)en_US
dc.subject.healththesaurusSURVIVAL ANALYSISen_US
dc.subject.healththesaurusNEW ZEALANDen_US
dc.subject.healththesaurusENTERAL NUTRITIONen_US
dc.subject.healththesaurusPICC LINE REMOVALen_US
dc.subject.healththesaurusNECROTIZING ENTEROCOLITISen_US
dc.identifier.doi10.24953/turkjped.2017.01.004en_US
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