Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/1008
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHurley, James C.*
dc.date.accessioned2017-02-19T23:42:27Znull
dc.date.available2017-02-19T23:42:27Znull
dc.date.issued2016en
dc.identifier.govdoc00964en
dc.identifier.issn1471-2334*
dc.identifier.urihttp://hdl.handle.net/11054/1008null
dc.description.abstractBACKGROUND: Acinetobacter species such as Acinetobacter baumanii are of increasing concern in association with ventilator associated pneumonia (VAP). In the ICU, Acinetobacter infections are known to be subject to seasonal variation but the extent of geographic variation is unclear. The objective here is to define the extent and possible reasons for geographic variation for Acinetobacter associated VAP whether or not these isolates are reported as Acinetobacter baumanii. METHODS: A meta-regression model of VAP associated Acinetobacter incidence within the published literature was undertaken using random effects methods. This model incorporated group level factors such as proportion of trauma admissions, year of publication and reporting practices for Acinetobacter infection. RESULTS: The search identified 117 studies from seven worldwide regions over 29 years. There is significant variation in Acinetobacter species associated VAP incidence among seven world-wide regions. The highest incidence is amongst reports from the Middle East (mean; 95 % confidence interval; 8.8; 6 · 2-12 · 7 per 1000 mechanical ventilation days) versus that from North American ICU's (1 · 2; 0 · 8-2 · 1). There is a similar geographic related disparity in incidence among studies reporting specifically as Acinetobacter baumanii. The incidence in ICU's with a majority of admission being for trauma is >2.5 times that of other ICU's. CONCLUSION: There is greater than fivefold variation in Acinetobacter associated VAP among reports from various geographic regions worldwide. This variation is not explainable by variations in rates of VAP overall, admissions for trauma, publication year or Acinetobacter reporting practices as group level variables.en
dc.description.provenanceApproved for entry into archive by Gemma Siemensma (gemmas@bhs.org.au) on 2017-02-19T23:42:27Z (GMT) No. of bitstreams: 0en
dc.description.provenanceSubmitted by Gemma Siemensma (gemmas@bhs.org.au) on 2016-12-12T23:03:14ZNo. of bitstreams: 0en
dc.description.provenanceMade available in DSpace on 2017-02-19T23:42:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2016en
dc.publisherBioMed Centralen
dc.titleWorld-wide variation in incidence of Acinetobacter associated ventilator associated pneumonia: a meta-regression.en
dc.typeJournal Article*
dc.type.specifiedArticleen
dc.bibliographicCitation.titleBMC Infectious Diseasesen
dc.bibliographicCitation.volume16en
dc.bibliographicCitation.issue577en
dc.bibliographicCitation.stpage1en
dc.bibliographicCitation.endpage12en
dc.publisher.placeLondon, UKen
dc.subject.healththesaurusACINETOBACTERen
dc.subject.healththesaurusACINETOBACTER INFECTIONSen
dc.subject.healththesaurusINCIDENCEen
dc.subject.healththesaurusMIDDLE EASTen
dc.subject.healththesaurusVENTILATOR ASSOCIATED PNEUMONIAen
dc.subject.healththesaurusRESPIRATION, ARTIFICIALen
dc.subject.healththesaurusINTENSIVE CARE UNITSen
dc.date.issuedbrowse2016-01-01-
dc.identifier.doi10.1186/s12879-016-1921-4en
Appears in Collections:Research Output

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.