Please use this identifier to cite or link to this item: http://hdl.handle.net/11054/578
Title: Combined SPECT/CT improves detection of initial bone invasion and determination of resection margins in squamous cell carcinoma of the head and neck compared to conventional imaging modalities.
Authors: Kolk, A.
Schuster, T.
Lange, Peter
Scheidhauer, K.
Kesting, M.
Bissinger, O.
Schwaiger, M.
Dinges, J.
Weitz, J.
Issue Date: 2014
Publisher: Springer
Place of publication: Berlin
Journal title: European Journal of Nuclear Medicine and Molecular Imaging
Volume: 41
Issue: 7
Start Page: 1363
End Page: 1374
Abstract: A longitudionally evaluated group of 30 patients with biopsy-proven HNSCC adjacent to the mandible underwent 99mTc-bisphosphonate SPECT/CT, MRI, MSCT and conventional radiography before partial or rim resection of the mandible was performed. In conclusion hybrid SPECT/CT was shown to have a higher specificity as it provided additional information about the existence and local extent of malignant bone infiltration of the madible. The sensitivivity of conventional SPECT is similar to that of SPECT/CT but the latter provides a much better delineation of the local tumour-bone contact area. Based on this information, surgical intervention of the rim versus partial resection can be planned and performed more precisely. Patient outcome can be improved by avoiding undertreatment and unnecessary or overextended bone resections.
URI: http://hdl.handle.net/11054/578
ISSN: 1619-7070
Internal ID Number: 00548
Health Subject: RADIOGRAPHY
COMBINED SPECT/CT
MULTISLICE CT
HIGH-RESOLUTION MRI
SCINTIGRAPHY
ANATOMICAL IMAGING
MAGNETIC RESONANCE IMAGING (MRI)
DIAGNOSTIC RADIOGRAPHY
MANDIBULAR BONE INVASION
SQUAMOUS CELL CARCINOMA
Type: Journal Article
Article
Appears in Collections:Research Output

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